Route 495 Life Science & Lab Space
The Route 495 corridor offers one of the most cost-effective options in the Greater Boston life science market, particularly for companies that need large footprints or manufacturing capabilities. Stretching through communities like Marlborough, Westborough, Devens, and Franklin, the area features a mix of flex, industrial, and purpose-built lab space suited for biotech, pharma, and advanced manufacturing users. With lower rents, abundant parking, and room to expand, Route 495 is especially attractive to later-stage companies and production-focused operations that want to stay in Massachusetts while managing occupancy costs and scaling efficiently.
Explore available life science and lab space in Route 495 ranging from 50 to 5,000 square feet - a practical size for startups, early-stage companies, and growing research teams. These footprints give emerging life science organizations the flexibility, functionality, and manageable scale needed to launch experiments, validate technology, and move towards commercialization.
Not sure how much lab space your team actually needs? We’ll help you assess square footage requirements based on your research type, equipment, staffing, and growth outlook. If you require more than 5,000 SF in Route 495 or surrounding Massachusetts submarkets, our advisors can connect you with additional opportunities that match your requirements.
Explore properties or contact our team to identify the lab space solution that best supports your needs.
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Frequently Asked Questions
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Life Science Properties, also known as laboratory or biotech properties, are specialized commercial properties designed to support the research, development, and production of life sciences, including biotechnology, pharmaceuticals, and medical devices. These properties typically feature state-of-the-art laboratory and research facilities, as well as office and shared communal space, and are often used by companies and organizations involved in research and development (R&D) activities. They are configured for either multi-tenant or single-tenant occupancy.
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For “start-up” sized firms seeking immediate space, our clients plan on a minimum of 60 days from our service engagement to conduct a market search, orchestrate a competition among a short-list of finalist properties, enter into a letter of intent, negotiate a lease or license agreement, move-in and start up operations. For larger firms (2,000-5,000 sf) opening or relating an existing operation, 6 months is typically a workable time from a to complete the above tasks.
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When searching for a Life Science Property for lease, key features to look for include state-of-the-art laboratory and research facilities, office space, shared and communal space and amenities such as higher structural clearances, truck access and loading, specialized ventilation and mechanical systems, high-capacity electrical infrastructure, emergency back-up power, and advanced security systems. The property should also be located in an area with access to top talent, research institutions, and other life sciences companies.
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While Life Science Properties are primarily designed to support R&D activities, they can also be used for other purposes, such as manufacturing, testing, and quality control. However, the property's specialized features and equipment may limit its use for other purposes, and any modifications or renovations may be subject to regulatory approvals and compliance with industry standards.