San Mateo County Life Science & Lab Space

Discover available life science and lab space in San Mateo County ranging from 0 to 5,000 square feet - the ideal size for startups, early-stage companies, and growing teams. These smaller footprints are designed to give emerging life science organizations the flexibility and functionality they need to launch, test, and scale.

Not sure how much lab space your company needs? We can help you evaluate the right square footage based on your research, team size, and growth plans. If you’re looking for space beyond 5,000 SF in San Mateo County, our advisors can connect you with additional properties that fit your requirements.

Explore the properties below, or contact our team to find the right lab space solution for your business.


Commercial building with solar panels on the roof and a sign for a physical therapy clinic called Progressive Motion.

San Mateo Building 1401

Rentable square footage available: ± 1,650
Lab benching on ground floor with sink and chemical fume hood

Aerial view of a commercial area with solar panels on rooftops, surrounded by trees and parking lots, under a partly cloudy sky.

San Mateo Building 1403

Rentable square footage available: ± 2,333
Enclosed lab with dedicated air & fume hood

A medical building with the sign 'Satellite Healthcare,' parking lot with cars, trees, and a clear sky.

San Mateo Building 1405

Rentable square footage available: ± 2,907
200 amps power, generator, large cell culture room, lab benches

A modern blue glass skyscraper with the logo 'SmartBay' on top, located near green hills and a parking lot with a fountain in the foreground.

San Mateo Building 1407

Rentable square footage available: ± 5,000
Class A lab, fume hoods, centrifuges, freezers, liquid nitrogen storage

Modern multi-story office building with glass windows and a landscaped front yard, located on a busy street with cars and trees.

San Mateo Building 1402

Rentable square footage available: ± 4,283
16 BSL2 lab benches, fume hood, sink, lab support room

Modern office building with large glass windows, several trees, and a parking lot with marked accessible spaces

San Mateo Building 1404

Rentable square footage available: ± 5,000
GENESIS premier life science project, biology and chemistry capable

Modern two-story commercial building with large glass windows and a decorative metal facade near the entrance, located at 1440. Clear blue sky and some greenery and parked bikes and cars in front.

San Mateo Building 1406

Rentable square footage available: ± 2,555
Bio labs, tissue culture space, shared vivarium, backup generator

A modern, two-story commercial building with a gray facade and blue accents, housing O. Bio, as indicated by the blue signage. The building is situated on a street corner with a sidewalk, some trees, plants, and outdoor seating nearby, under a partly cloudy sky.

San Mateo Building 1408

Rentable square footage available: ± 4,369
1200 amps, 5 roll-up doors, enclosed hardware tech testing area

FAQs

  • Life Science Properties, also known as laboratory or biotech properties, are specialized commercial properties designed to support the research, development, and production of life sciences, including biotechnology, pharmaceuticals, and medical devices. These properties typically feature state-of-the-art laboratory and research facilities, as well as office and shared communal space, and are often used by companies and organizations involved in research and development (R&D) activities. They are configured for either multi-tenant or single-tenant occupancy.

  • For “start-up” sized firms seeking immediate space, our clients plan on a minimum of 60 days from our service engagement to conduct a market search, orchestrate a competition among  a short-list of finalist properties, enter into a letter of intent, negotiate a lease or license agreement, move-in and start up operations. For larger firms (2,000-5,000 sf) opening or relating an existing operation, 6 months is typically a workable time from a to complete the above tasks.

  • When searching for a Life Science Property for lease, key features to look for include state-of-the-art laboratory and research facilities, office space, shared and communal space and amenities such as higher structural clearances,  truck access and loading,  specialized ventilation and mechanical systems, high-capacity electrical infrastructure, emergency back-up power, and advanced security systems. The property should also be located in an area with access to top talent, research institutions, and other life sciences companies.

  • While Life Science Properties are primarily designed to support R&D activities, they can also be used for other purposes, such as manufacturing, testing, and quality control. However, the property's specialized features and equipment may limit its use for other purposes, and any modifications or renovations may be subject to regulatory approvals and compliance with industry standards.